Commercial Property for Sale in Missouri

Commercial Only shows 29 active listings for sale here from participating MyStateMLS brokerages. This is not every commercial property on the market in the area.

By type: commercial land (9), office (6) and industrial (3). Common reported features: parking reported (4), accessibility features reported (3) and grade-level or drive-in doors (2). Many listings are in or near Chillicothe, Neosho and Cameron.

Median asking price of the 29 listings with a stated price: $335,000 (range $125,000 to $4,500,000). Asking prices on this site only, not sold prices or the whole market; auctions excluded; updated Nov 3, 2026.

Open map and filtersSpace for lease here
Photo 1 of 10, commercial property at 000 Dolphin Drive, Neosho, MO 64850
For sale

$840,000

Commercial land

157 acres

$5,344/acre (asking price ÷ land area)

000 Dolphin DriveNeosho, MO 64850

Listing courtesy of Show Me Real Estate · MyStateMLS #12045881

Photo 1 of 16, commercial property at 323 N Main St, Cameron, MO 64429
For sale

$130,000

Office building

1,547 SF building0.05 acres lot

$84/SF (asking price ÷ building area)

323 N Main StCameron, MO 64429

Listing courtesy of The OConnor Agency - United Country Real Estate · MyStateMLS #12042686

Photo 1 of 8, commercial property at 8680 Highway 67, Fredericktown, MO 63645
For sale

$225,000

Commercial property

11 acres

  • Grade-level or drive-in doors

8680 Highway 67Fredericktown, MO 63645

Listing courtesy of National Land Realty, Eastern MO · MyStateMLS #12034608

Photo 1 of 60, commercial property at 0000 E Heller Rd, Columbia, MO 65202
For sale

$4,500,000

Commercial property

189 acres

0000 E Heller RdColumbia, MO 65202

Listing courtesy of BigIron Realty · MyStateMLS #12048201

Photo 1 of 11, commercial property at 52127 River Rd, Milan, MO 63556
For sale

$180,000

Commercial property

11,264 SF building2.6 acres lot

$16/SF (asking price ÷ building area)

52127 River RdMilan, MO 63556

Listing courtesy of Graham Agency LLC · MyStateMLS #12011786

Photo 1 of 2, commercial property at 101 S. Frame Street, Hamilton, MO 64644
For sale

$335,000

Office building

2,432 SF building

$138/SF (asking price ÷ building area)

101 S. Frame StreetHamilton, MO 64644

Listing courtesy of RE/MAX Town and Country · MyStateMLS #11972166

Photo 1 of 9, land at 000 Dolphin Drive, Neosho, MO 64850
For sale

$840,000

Commercial land

157 acres

$5,344/acre (asking price ÷ land area)

000 Dolphin DriveNeosho, MO 64850

Listing courtesy of Show Me Real Estate · MyStateMLS #12045899

Photo 1 of 21, multifamily property at 415 Harvester Road, Chillicothe, MO 64601
For sale

$690,000

Industrial property

17,500 SF building1.3 acres lot

$39/SF (asking price ÷ building area)

  • Dock-high doors
  • Grade-level or drive-in doors

415 Harvester RoadChillicothe, MO 64601

Listing courtesy of United Country Graham Agency, LLC · MyStateMLS #11962473

Photo 1 of 7, multifamily property at 0 Rt-190, Lock Springs, MO 64654
For sale

$390,000

Multifamily property

0.52 acres

0 Rt-190Lock Springs, MO 64654

Listing courtesy of United Country Graham Agency, LLC · MyStateMLS #11962420

Photo 1 of 4, multifamily property at 720 Harvester Road, Chillicothe, MO 64601
For sale

$290,000

Multifamily property

0.51 acres

  • Elevator

720 Harvester RoadChillicothe, MO 64601

Listing courtesy of United Country Graham Agency, LLC · MyStateMLS #11962312

Taney Co Commercial For Sale
For sale

$374,900

Special-purpose property

4,000 SF building0.8 acres lot

$94/SF (asking price ÷ building area)

  • Kitchen hood or grease trap
  • Signage

13879 Us Highway 160Forsyth, MO 65653

Listing courtesy of Red Cedar Land Company · MyStateMLS #12027001

Photo 1 of 44, commercial property at 9741 Gateway Drive, Neosho, MO 64850
For sale

$159,900

Industrial property

2,400 SF building0.87 acres lot

$67/SF (asking price ÷ building area)

  • Parking reported

9741 Gateway DriveNeosho, MO 64850

Listing courtesy of Show Me Real Estate · MyStateMLS #11948905

Photo 1 of 12, commercial property at 0 E State Hwy A, Ridgeway, MO 64481
For sale

$599,000

Commercial land

25 acres

$23,960/acre (asking price ÷ land area)

0 E State Hwy ARidgeway, MO 64481

Listing courtesy of National Land Realty, Eastern MO · MyStateMLS #11943015

Photo 1 of 8, commercial property at 14685 Clayton Rd, Ballwin, MO 63011
For sale

$375,000

Commercial land

0.99 acres

$378,788/acre (asking price ÷ land area)

14685 Clayton RdBallwin, MO 63011

Listing courtesy of National Land Realty, Eastern MO · MyStateMLS #11946963

Photo 1 of 35, commercial property at 425 & 437 Cherry Street, Chillicothe, MO 64601
For sale

$475,000

Retail property

4,848 SF building0.51 acres lot

$98/SF (asking price ÷ building area)

  • Kitchen hood or grease trap
  • Parking reported

425 & 437 Cherry StreetChillicothe, MO 64601

Listing courtesy of United Country Graham Agency, LLC · MyStateMLS #11878492

Photo 1 of 32, commercial property at 15290 Hwy 135, Boonville, MO 65276
For sale

$1,425,000

Office building

6 acres

15290 Hwy 135Boonville, MO 65276

Listing courtesy of Farmland Consultants LLC · MyStateMLS #11863532

Photo 1 of 27, commercial property at 54.21 +/- Acres Monticello Court, House Springs, MO 63051
For sale

$560,000

Commercial land

54 acres

$10,330/acre (asking price ÷ land area)

54.21 +/- Acres Monticello CourtHouse Springs, MO 63051

Listing courtesy of National Land Realty, Eastern MO · MyStateMLS #11862873

Photo 1 of 21, commercial property at 000 Hwy 136, Memphis, MO 63555
For sale

$239,900

Commercial property

3 acres

000 Hwy 136Memphis, MO 63555

Listing courtesy of Hometown Real Estate / Pioneer Land Company · MyStateMLS #12036394

Photo 1 of 33, commercial property at 607 & 609 Jackson Street, Chillicothe, MO 64601
For saleReduced $10,000

$315,000

Mixed-use property

4,936 SF building0.14 acres lot

$64/SF (asking price ÷ building area)

607 & 609 Jackson StreetChillicothe, MO 64601

Listing courtesy of United Country Graham Agency, LLC · MyStateMLS #11779348

Photo 1 of 5, commercial property at 633 N Point Prairie Road, Wentzville, MO 63385
For sale

$1,350,000

Commercial land

3.17 acres

$425,868/acre (asking price ÷ land area)

633 N Point Prairie RoadWentzville, MO 63385

Listing courtesy of National Land Realty, Eastern MO · MyStateMLS #11798541

Photo 1 of 14, commercial property at 101 High, Stockton, MO 65785
For saleReduced $9,500

$155,000

Commercial property

2,818 SF building0.4 acres lot

$55/SF (asking price ÷ building area)

  • Corner location
  • Parking reported

101 HighStockton, MO 65785

Listing courtesy of English Creek Realty, LLC · MyStateMLS #11740851

Photo 1 of 48, commercial property at 33 W Olive St, Aurora, MO 65605
For sale

$241,000

Commercial property

33 W Olive StAurora, MO 65605

Listing courtesy of Country Vision Associates · MyStateMLS #11678273

Photo 1 of 26, commercial property at 2667 Nw Hwy 7, Clinton, MO 64735
For sale

$325,000

Office building

1,500 SF building2.1 acres lot

$217/SF (asking price ÷ building area)

2667 Nw Hwy 7Clinton, MO 64735

Listing courtesy of America's Land Partners - Missouri · MyStateMLS #11677567

Photo 1 of 60, commercial property at 3711 N Us Hwy 63, West Plains, MO 65775
For sale

$1,800,000

Industrial property

4.93 acres

3711 N Us Hwy 63West Plains, MO 65775

Listing courtesy of BigIron Realty · MyStateMLS #11739043

Counties in Missouri

Counts include every property type in the county; the linked page shows all of them.

Cities and towns in Missouri

Listings provided by MyStateMLS and shown with the listing brokerage's name. Counts and figures describe listings displayed on Commercial Only only. Property types and features describe what each listing reports; see how listings qualify. Information is deemed reliable but not guaranteed.